Saturday, October 16, 2021

NYU and NYU Abu Dhabi researchers develop a new artificial intelligence tool to improve the accuracy of breast cancer detection

Abu Dhabi, UAE, September 24, 2021: Ultrasound continues to be a critical tool, often in conjunction with mammography, for the screening, detection and characterization of breast cancer. However, ultrasound can have high false-positive rates, which then lead to unnecessary biopsies, increased costs, and discomfort to patients. In a new study, a team of researchers from NYU and NYU Abu Dhabi report that they have developed a novel artificial intelligence (AI) system that achieves radiologist-level accuracy in identifying breast cancer in ultrasound images. The system, designed to be a decision support tool for clinicians, also helped radiologists significantly decrease their false positive and requested biopsy rates while maintaining the same level of sensitivity.

Abu Dhabi, UAE, September 24, 2021: Ultrasound continues to be a critical tool, often in conjunction with mammography, for the screening, detection and characterization of breast cancer. However, ultrasound can have high false-positive rates, which then lead to unnecessary biopsies, increased costs, and discomfort to patients. In a new study, a team of researchers from NYU and NYU Abu Dhabi report that they have developed a novel artificial intelligence (AI) system that achieves radiologist-level accuracy in identifying breast cancer in ultrasound images. The system, designed to be a decision support tool for clinicians, also helped radiologists significantly decrease their false positive and requested biopsy rates while maintaining the same level of sensitivity.

NYUAD Assistant Professor Emerging Scholar of Computer Engineering Farah Shamout and colleagues at NYU detail their findings in “Artificial intelligence system reduces false-positive findings in the interpretation of breast ultrasound exams,” a paper published in the journal Nature Communications.

The researchers utilized a dataset of more than 280,000 ultrasound exams from over 140,000 patients examined at NYU Langone Health between 2012 and 2019 to develop and test their new system. The system is designed to identify malignant lesions in breast ultrasound images, with the primary goal of reducing the frequency of false positive findings. It can detect cancer by assigning a probability for malignancy and highlighting parts of ultrasound images that are associated with its predictions.

To understand the potential value of this novel AI system in a clinical setting, the researchers conducted a reader study to compare its diagnostic accuracy with ten board-certified breast radiologists. It achieved higher accuracy than the ten radiologists on average, but a hybrid model that aggregated the predictions of the AI system and radiologists achieved the best results in accurately detecting cancer in patients. The performance of the AI system remained robust across patients from different age groups and mammographic breast densities.

“Our findings highlight the potential of AI to improve the accuracy, consistency, and efficiency of breast ultrasound diagnosis,” said Dr. Shamout. “Importantly, AI is not a replacement for the expertise of clinicians. However, the powerful, complimentary role that AI systems can play as a decision support tool leads us to believe that they should and will be increasingly translated into clinical practice.”

Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths among women worldwide.

About NYU Abu Dhabi

NYU Abu Dhabi is the first comprehensive liberal arts research campus in the Middle East to be operated abroad by a major American research university. NYU Abu Dhabi has integrated a highly selective undergraduate curriculum across the disciplines with a world center for advanced research and scholarship. The university enables its students in the sciences, engineering, social sciences, humanities, and arts to succeed in an increasingly interdependent world and advance cooperation and progress on humanity’s shared challenges. NYU Abu Dhabi’s high-achieving students have come from over 115 countries and speak over 115 languages. Together, NYU’s campuses in New York, Abu Dhabi, and Shanghai form the backbone of a unique global university, giving faculty and students opportunities to experience varied learning environments and immersion in other cultures at one or more of the numerous study-abroad sites NYU maintains on six continents.


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